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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4460122db3e92a51fed95677b62cd977cd8ba42f547efcd021730c6de8954082' 
  AND token = '8Px19BEmctbb0EP/9TEhhKlo1HWC17mrxe8Z/L47J/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}