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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b75c798b60ee23831b6de5170899ad30761bc5f54703021817abe198c0c37fb' 
  AND token = 'PTlxMrmFx2IYmm3Xoje4Y5Yb0HIt+yXXm3j0btl4q54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}