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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf147de1505e3f1d04982a3746119915ddba6cb1cd9bb2d27d84aa29ef6ea49' 
  AND token = 'yAzg+mUuYp8gs9c0A4eHbAU+tInvdl9JoSOXKYFOiOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}