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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b53e30e60107e74294b27c00a58d77c4532b80e5800abadbe139b587f479976' 
  AND token = 'mMlmb7qKezxv89MUYIe4/6/F+ItI+N0UTmCUH96CX3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}