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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492640f3456922cb8640743ce75c5c8527803c3ed2cdc5268f21f4dacd1a329e' 
  AND token = 'udbe1yx1Rf7ViBsk0SlcWfH9v65VT22CPJJmiI0/45A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}