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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6993d6a0b9ebef8a52a91c1e246e860ae2052ec52430b3c8dec91f9d4b8d495' 
  AND token = 'OaB0DsWFQHnqzxG4piFoOyXxzC5c2Np91VaNnwXIdt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}