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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad67a1b0d3b29fecf0d02866ae34455d95f3e8b82aa8aa62851b9c357c69cb12' 
  AND token = 'GtAVFtTG9Km6JuLFnSeSz4psj5zuPxmOdPaHqPyPEFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}