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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84909a4c47b0cee5c3f0d3006402a0bfeaec6a0d4da05bae8206a959bded4f0d' 
  AND token = 'RL1GhhxSe16HBQYzIW8dyWuRQ6ExBad0W3iuzLcbHc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}