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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c074cf394b38aa5f3b66b9733d760994aa79c4d7e0bf43ca63254fada435da' 
  AND token = 'QlCZ2LDFnZy+M/ohBrYYxaH9hVSMLd9BL4RU3Gu9H5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}