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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7258523168cdb318f1e0514889d7235270286ad66a321918c3cd642b65d11bb3' 
  AND token = 'QK3WAIwiIbWK3uuxOpAT0UmQCKe5CnNJJxSnLFn2rh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}