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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78586dc00019c9d1398cd5594c471026968789cc0b2e1834825bd430d63882d7' 
  AND token = 'D62VZDm+UKT7cZGLYemZ4kygvUESy4ydij1depDCvU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}