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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cbe100e50c9ac46f4a9a229fd442a32037703ab0cd7de8afc6e3f13231d622d' 
  AND token = 'VM53YI/8WRwUu3bzZyLU0tVPc+TySwb1qHSTu7sUqX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}