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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ebe22eeef3a94d44d7a989a82fe48157fe1ba2544f7221d820a3fac9175b41' 
  AND token = 'FeGT9Zea+brk0wzwmyP6NStIoTU3jCQY8rZ39IC+EQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}