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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e60d67af11bd6c5f4f89f37ac5b4f8e783b8fd127a9d21c275f254c5b2b37be' 
  AND token = 'CNar/iPrE9+ScmAr77b0wXvtM3qt/yyjKGY6uL1lg7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}