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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f31d3cdbd2701751257fd83619a3ffa161a0a2af5ebe42121ced400c89163f7d' 
  AND token = 'EFNtumt5rRrdfyi6HZ+eAVfnLQ9xuJM7AItbn5qd5Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}