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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c73fc646afc2bdcdc19a2905ac644315c1b420b097c8f9842f1325b68b26a23' 
  AND token = '1HehaIzejPPDNTo2D5V95Myi0xuxSq4A05fxUExQAP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}