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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc1a8d5846d8160887e8cb35e4820c92e39ede9df47e3a0875777bf92df5f41' 
  AND token = '/qulxOTYCaUm25PIreMmyYMJW1scaaeJvRatbDjmH+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}