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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64a45e0af74a2da2fe0e926290ec99cf4a32e8019e57f882c259801d87f2f0b' 
  AND token = 'Sa+Pl6W4TvZR/SeXq0LS5HDZqojMPtg/2rpCdBuXnig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}