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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8caed3898af6579ddae54aa8191078579b63532a8b5aaeb74bacdc213d0f6bd' 
  AND token = '7W7kP5dsGkfdEuUSj+8NDhRU3q0KN5c6QBNIrUwZzf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}