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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4452c18d6febe892a71e85f5a91f676a84677e44b31faf5bf1d54989ac3819f' 
  AND token = 'yx2mAJuQxuJ8AqD2YzAJc3dkbrZ3hvmAYA5AUWyZRZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}