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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c69c7070a864bd32e0bdc46e31f8a3f65236b4f4eaaf674dd17c178f113326' 
  AND token = 'qSdyf8U6SSlL/4GWr7t96s/uUyTGTMXQEOz/Bk5l3Ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}