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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e54787e0255a4b226bfaa8ffa52596e27701cc8cb74da327ccf356c56c88b3' 
  AND token = 'crzMnC5JN3E6ByT+MEKrTXqDVkK/io+2gHAz9+YY0Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}