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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9334610d210d4193a57fe58e5ce57b15b3115b7f6f7eb800366ef884983eaa6a' 
  AND token = '3+M83LWv3WIpcsu0eLWVvkOHwejTtn2orWHMx9V+6Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}