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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fab0be25afcf96eee76212feb28f3b34eeff4010b4645ab2c8ef4b5859c138' 
  AND token = 'nORqJdpR1tMG8YnZgihhwzt+V06saOWiS3cgJmJXhJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}