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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c771d3fd8cd9b24d1a237befb3868be5cf693823693b2673027f49dc601b339' 
  AND token = '5AeoTJt0vLoCgUhqi60xUHAEj80wznRtQWpCFCWIcac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}