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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee0029550dbd78eab49be741a6b834480d41d16230443ca7287075cd3536572' 
  AND token = 'cU816T3Ope1Qt2KPSfaaEVL/31MRwuALTBnKSMRR7IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}