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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a32f729766e6ae70bbfa94451ba10571c9e7191fa2da7f16677f2d159274965e' 
  AND token = '1xaE0HYQTWd3Ql8wSCVsqEj3XA09tWY58WxC+05ImhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}