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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42fe8e0e061b0478651b81e4fb182a3a3a84d98b0acef767028cd22143f2867' 
  AND token = 'HyANMY7MbIDuPZtmGTlxR6VCYgoTvdOV7VSHNInq7Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}