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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca2c64e3f8aabe1aaef30300ef9cfc9001beb06a7fd9f29d3370eecd00e4899' 
  AND token = '3qLSSX8FloxP6NwUR6Rz3/hqV6dFlwGhyCo3iEFn0ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}