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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fecd12a62a4f6b9b65758b8edae7254675d74d9a51a9747d6b06b7b8df1411' 
  AND token = '6rQilqjYDPvPuCMLsLUHHZH8/4JpnQSPoPzuWQ5Tej0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}