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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d96af6520d284646d7cfdd50f9d17569de7d340b241374812cea8187a00d8f' 
  AND token = '4zRaAo+pKqFfXtOaHEY/60xz0ZwCho4T2e/QYvCsf00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}