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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af72336c89deffa109cc953c292f8279757a87086d9b20d60b2a5300f867e7f' 
  AND token = 'r2aB/whOb8JSnuq2+FrHvHzhd9HWUtBV8K2mdnRqDwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}