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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b73362f18883dd26cfcad7b2b7147f8b3dd538b364fb710bb76f0052b3072a3' 
  AND token = '4RIvoh69apeuvAdYoxoj+pzRiEYgSASHH4tvtr3z8BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}