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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f0633e681a60628eb027b814c6111a111b3f0de14b7defbece095de2f950ca' 
  AND token = 'A9z7Zzvzmbmf77N2/4Ho0R6z32OOLBH3zXeu3AVJjYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}