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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c004b4afa130bd96d24be8fdff3d4a37c7e59120f859d1606d9e7c16b555281e' 
  AND token = 'cbfKSPgY1+mzpt0haXso4uzxAK9j8JzOaYHX1na+WT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}