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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b60a7ec14370fbc12ab4bcba7f7352db0ec39f96c57f4d3b99e082fa445f2b4' 
  AND token = 'lJMVlvr5xh4sUCj0WNhFR5eRQsDnMEVDuPCIGYq9vu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}