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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad065936495a88207242834ebab63e5373d06d14f921c9fc8564e906a2966019' 
  AND token = 'nXCMHZDObTMpOv0OT503UaB3i+Rw0xReRlfufXKKp5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}