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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3920effd8246f74da92e59721d06d625b692bde00742a582f129142628691644' 
  AND token = '1Bo4YBDtM4Wq111yRhTdIh4XdOUfLTF5k2iC4c3U22Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}