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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48536244e5943d428d6a589fc17e2e4dfb894f9e015680013461e21b10388bf7' 
  AND token = '398SDtmSp7geQmGXttszx5m7hsvvG319aDblhmbblaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}