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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0442b9dc530e34e959a6cc424edb95a765c0c0c6fdc6389d14e84d8ebd255a7c' 
  AND token = 'SI26E1fR8SkZUq04kZJv8hRuLACVUZuExTybives9W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}