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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0181e4cf3e2be74299ba4f51663fcf348bf4b523386dde800f354bea95c3ffb8' 
  AND token = 'X1YdOgmiuoJi83jFd4ruUeyn2sZwtQJAEjadojYll24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}