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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24dcc178409d08f2ee69c4b594640c3a78ea7fdc0b7783399b8c1e8cfb643c62' 
  AND token = 'lE0SqhatxNIa6VWAx/YGlAVlTivt3e5ns0wW6Ns23r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}