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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbe2107ef9080ff0f7e6b61dc60c6e8291864d1263c0d0b3937cf070fa46885f' 
  AND token = '35ar2Eo7A/W7l+a/+nBZCZPLvEcYx9ChrRhp68qwgZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}