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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a0c7f99a075d9838b2e12c10dfa4c71469827f85ca211ca5a2d677d3afdca7' 
  AND token = 'NLj6jVlppgx4+WtS1mvT5/x0F0GXwo8IPwWKMy+qk0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}