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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad5e4c93360248070d7eb290a01f0917ad7c475cafba626737680fdaec869af' 
  AND token = 'Mly5W2irbdN10uBxrr/NLWsegXs8c/Sm4rEFtt4v+3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}