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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b8f123da1ad27fb240e6621d8e43312c383ef6938a62a7686a2a8d3219ceed' 
  AND token = 'qx4cnV8OxZ6sXdfyXHv3/H1wKNvirAuqaFdNZzeT3ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}