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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6315c542c1c1d722a3b163b5010e94c24818609e5c6cbfddb1d0b65e4b4f446' 
  AND token = 'sNtdOBbQ7He+Kbr0r78JY81dJn1wUBSQ52Dj0Pz+GKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}