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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46714cf1fb5d33a66062c4fcdcf5d656a7145136b3156b2f3c921ade00ec30d3' 
  AND token = 'thEkMy3DI3rc7Q3hAw/j77GFiotn4uUPc/BVSe7XzNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}