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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b75fe2c12487a8c967cf64abbd4eab8326a21bcdb18d3e6bc2d66e57be471a8' 
  AND token = 'A+kb0T/QA7pxxINV/3OgTov96hdLE/e8j02Ty3JQ5xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}