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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c8a60f709422056862f0a057d851d91c8ee301e031cba58970d9170b4c4d9b' 
  AND token = 'KJD/MKwb9eToTAVzJYBDrMKZ0KzWMHqc5ypJgwTKSIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}